NMN (nicotinamide mononucleotide) is a compound that is naturally produced in the body and is essential for cellular function. It is a precursor to NAD+ (nicotinamide adenine dinucleotide), which is a coenzyme that plays a role in many important cellular processes, including energy production, DNA repair, and cell signaling.
As we age, our levels of NAD+ decline. This decline is thought to contribute to age-related diseases and decline in physical and cognitive function. NMN supplements can help to increase NAD+ levels, which may have a number of benefits for health and longevity.
Studies in animals have shown that NMN supplementation can extend lifespan, improve physical function, and protect against age-related diseases such as heart disease, cancer, and Alzheimer's disease. For example, one study in mice found that those who were given NMN lived an average of 10% longer than those who were not given NMN. The mice who were given NMN also had improved muscle strength, endurance, and glucose metabolism.
Studies in humans are still in their early stages, but some early research suggests that NMN supplementation may also have benefits for human health. For example, one study in humans found that those who were given NMN had improved insulin sensitivity and blood sugar control. Another study found that NMN supplementation improved cognitive function in people with mild cognitive impairment.
Overall, the research on NMN is promising and suggests that it may have a number of benefits for health and longevity. However, more research is needed to confirm these findings and to determine the optimal dose and safety of NMN supplementation.
Here are some of the ways that NMN supplements may extend life:
Increase NAD+ levels. As mentioned above, NAD+ is a coenzyme that plays a role in many important cellular processes. As we age, our levels of NAD+ decline. This decline is thought to contribute to age-related diseases and decline in physical and cognitive function. NMN supplements can help to increase NAD+ levels, which may have a number of benefits for health and longevity.
Activate sirtuins. Sirtuins are a family of proteins that have been shown to have anti-aging properties. They do this by regulating a number of important cellular processes, such as metabolism, DNA repair, and cell death. NMN can help to activate sirtuins, which may lead to a number of anti-aging benefits.
Reduce inflammation. Inflammation is a major factor in many age-related diseases. NMN has been shown to reduce inflammation in both animals and humans. This may be due to its ability to increase NAD+ levels, which has been shown to have anti-inflammatory properties.
Protect against DNA damage. DNA damage is a major cause of aging and age-related diseases. NMN has been shown to protect against DNA damage in both animals and humans. This may be due to its ability to increase NAD+ levels, which has been shown to have DNA repair properties.
Improve mitochondrial function. Mitochondria are the cells' "powerhouses" and are essential for energy production. As we age, our mitochondria become less efficient. This can lead to a decline in energy production and a number of other age-related problems. NMN has been shown to improve mitochondrial function in both animals and humans. This may be due to its ability to increase NAD+ levels, which is essential for mitochondrial function.
Overall, the research on NMN is promising and suggests that it may have a number of benefits for health and longevity. However, more research is needed to confirm these findings and to determine the optimal dose and safety of NMN supplementation.
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